Preface and Forward

• What Is a TIP?
• Buprenorphine Advisory Board
• Consensus Panel
• Foreword

Executive Summary

Chapter 1: Introduction

• Practical Guidelines for Physicians
• Opioid Addiction Today in the United States
• Current State of Opioid Addiction Treatment
• Current Pharmacotherapy Treatment Options for Opioid Addiction
• Buprenorphine: A New Treatment Option for Opioid Addiction
• Summary and Overview of the Guidelines

Chapter 2: Pharmacology

• General Opioid Pharmacology
• Pharmacology of Buprenorphine
• Buprenorphine Safety, Adverse Reactions, and Drug Interactions
• Effectiveness of Buprenorphine Treatment
• The Buprenorphine/Naloxone Combination
• Diversion and Misuse of Either Buprenorphine Alone or the
• Buprenorphine/Naloxone Combination Product
• Summary

Chapter 3: Patient Assessment

• Screening and Assessment of Opioid Use Disorders
• Determining Appropriateness for Buprenorphine Treatment

Chapter 4: Treatment Protocols

• Maintenance Treatment With Buprenorphine
• Opioid Detoxification With Buprenorphine
• Patient Management

Chapter 5: Special Populations

• Patients With Medical Comorbidities
• Pregnant Women and Neonates
• Adolescents/Young Adults
• Geriatric Patients
• Patients With Significant Psychiatric Comorbidity
• Polysubstance Abuse
• Patients With Pain
• Patients Recently Discharged From Controlled Environments
• Health Care Professionals Who Are Addicted to Opioids

Chapter 6: Policies and Procedures

• The DATA 2000 Waiver
• Preparing for Office-Based Opioid Treatment
• Confidentiality and Privacy
• Buprenorphine Use in OTPs

Appendix A -- Bibliography
Appendix B -- Assessment and Screening Instruments
Appendix C -- DSM-IV-TR Material
Appendix D -- Consent to Release of Information Under Title 42, Part 2, Code of Federal Regulations
Appendix E -- Clinical Toolbox: Chapter 3 Supplemental Information
Appendix F -- Fed. of State Medical Boards—Model Policy Guidelines for Opioid Addiction Treatment in the Medical Office
Appendix G -- Stages of Change
Appendix H -- Sample Treatment Agreement/Contract
Appendix I -- Glossary
Appendix J -- Field Review Panel

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES
Substance Abuse and Mental Health Services Administration
Center for Substance Abuse Treatment
5600 Fishers Lane
Rockville , MD 20857

Copies may be obtained free of charge from SAMHSA’s National Clearinghouse for Alcohol and Drug Information (NCADI), (800) 729-6686 or (301) 468-2600; TDD (for hearing impaired), (800) 487-4889, or electronically through the following Internet World Wide Web site:
http://www.samhsa.gov/centers/csat2002/publications.html